Symbol
Name
ID

Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
MGI:3041243

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

immune system phenotype

increased B cell apoptosis

decreased B cell proliferation

decreased T cell proliferation

increased susceptibility to induced colitis

abnormal thymocyte activation

abnormal class switch recombination

decreased B-1 B cell number

decreased B-1a cell number

absent marginal zone B cells

decreased B cell number

decreased IgG1 level

decreased IgG3 level

decreased IgG level

decreased IgM level

abnormal NK cell physiology

decreased interferon-gamma secretion

increased interferon-gamma secretion

increased interleukin-12 secretion

increased interleukin-12b secretion

decreased interleukin-2 secretion

increased interleukin-6 secretion

increased susceptibility to endotoxin shock

Availability

Mouse Genotype

Nfkbid^m1Btlr/Nfkbid^m1Btlr

Nfkbid^{tm1a(EUCOMM)Wtsi}/Nfkbid^{tm1a(EUCOMM)Wtsi}

Nfkbid^tm1Clay/Nfkbid^tm1Clay

Nfkbid^tm1Ktak/Nfkbid^tm1Ktak

Nfkbid^{tm1a(EUCOMM)Wtsi}/Nfkbid⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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